Vision Paper Research Example | Topics and Well Written Essays - 2000 words

Vision - Research Paper Example I have wanted my students to share with me what they cannot share with any other person because I do not want them to stay disturbed, which might affect their studies. I have wanted them to share their happiness with me and consider me as someone who cannot only guide them professional but also personally. However, one cannot achieve all that he wants but struggle can make everything possible and this is what I am doing to make my class room an idealistic place for all the students and teachers. Being a teacher is easy but to live teaching is not a child’s play, it requires a lot of patience and tolerance to fulfill the meaning of word teacher, to fulfill the expectations of parents and most importantly to fulfill the expectations of students. Teachers do not have their roles limited to the boundary of classrooms; their duty is far beyond the classrooms. If every teacher understands this concept then it would not be difficult for him or her to acquire the place of â€Å"Best Friend† in the hearts of students. Now the question must arises that why is there a need of being friends of students? This paper will gradually answer this question. Primarily, being friend of students can accomplish the vision of every teacher. Regardless of the desires mentioned in the vision, friendship with the students can achieve any vision the teachers have (Koplow, 2002). I am repetitively focusing on being friends because I have personally experienced this in my life that we are only easily able to share our life with those who understand us the most and in most of the cases, these are our friends. Friends know every aspect of our personality, they know our backgrounds, they are aware of our skills and capabilities, and they always do what makes us happy. I believe that only after acquiring this place in the hearts of students, I can accomplish my vision, which is to develop a culturally responsive classroom. Culturally responsive classroom reflects the idea

Cassatt, Mary Assignment Example | Topics and Well Written Essays - 1500 words

Cassatt, Mary - Assignment Example tend the influence of their tutors to their styles in canvas, Cassatt’s style was notably different from the one used by Degas (National Art Gallery). According to the National Art Gallery, Degas also introduced Cassatt in the asymmetrical styles employed by Japanese artists and the use of bright colors. The use of bright colors according to Web Museum demonstrated a mood of gentleness that served to brighten by her constant use of the â€Å"golden lighting.† These aspects worked in harmony with the family and children which was the dominant theme in most of her works. Cassatt was always a quick learner who learnt the basics about a particular style in art and instead of reproducing the same pieces, she would always ensure that she employed her innovativeness to come up with impressive masterpieces. The best example is her portrayal of the techniques she learnt from Japanese art for instance asymmetry and wood block print. She was able to mould these techniques in such a way that they fit so perfectly within her own impressionsim themes. The paper looks at one of the works of Cassatt, â€Å"The Little Girl in Blue Armchair† (Figure 1) in order to relate it with its historical context, to establish the impact it had during the historical context, and the importance of the piece in contemporary art. The Context in which the Work was made. The painting of the Little Girl in Blue Armchair was done in 1878 and it painted in an oil canvas. The painting depicted the image of a little girl relaxingly sprawled in a chair. As outlined by National Art Gallery, the work demonstrated the keen observation of Cassatt in the way she managed to emphasize and display on an aspect that would otherwise be considered subtle and inconsequential. Cassatt manages to display the innocence of the little girl as she sits in the chair in a childlike manner. In a unique fashion of impressionism art Mary managed to use color, everyday life and light to demonstrate the beauty in an otherwise

Embryonic And Induced Pluripotent Stem Cells Biology Essay

Embryonic And Induced Pluripotent Stem Cells Biology Essay INTRODUCTION: Stem cells are cells which are found in almost all multicellular organisms. Stem cells was proposed by a histologist Maksimov. A in 1908. They develop into many different types of cells in the body during their early life and growth and serve as a internal repair system in many tissues. Formation of new cells can be seen when stem cells division starts these new cells can either form a stem cell or other types of cells like muscle cells,brain and red blood cells with specialized functions. Stem cells are the objects in biomedical research and are differentiated from other types of cells by two main characteristics. Firstly, Stem cells are the undifferentiated cell types they possess the capacity of both self renewable during cell division. Secondly, Potency which means they can be differntiated into differnt types of specialized cells with specific function.(Bishop et.al., 2002). Stem cells can be totipotent and pluripotent. In some organs like gut or bone marrow the st em cells divide either to replace or repair the damaged or worn out tissues while in other organ system like pancreas they divide under some specific function Totipotent stem cells can give rise to a functional organism as well as to every cell type of the body. Pluripotent stem cells are capable of giving rise to any tissue type, but not to a functioning organism. Multipotent stem cells are more differentiated and thus can give rise only to a few tissue types. For example, a specific type of multipotent stem cell called a mesenchymal stem cell can produce bone, muscle, cartilage, fat, and other connective tissues. (Pittenger et.al., 1999). They are two types of Stem cells 1) Embryonic stem cells 2) Adult stem cells also known as somatic cell or tissue specific. Embryonic stem cells are derived from the blastocysts and are pluripotent instead of totipotent because they do not have the ability to become part of the extra-embryonic membranes or the placenta while the adult cells are present in adult tissues while the stem cells found in developed tissues are the Adult stem cells and the example for this is the hematopoietic stem cells of blood which cannot give rise to the cells of a different tissue, such as nerve cells in the brain (Frankel et.al.,1999). The difference between between embryonic and adult stem cells(somatic) is their origin that is embryonic cells can differntiate into any c ell types but adult stem cells are limited and can differentiate into the cells of their own tissue by this the grown cells wont be rejected by the immune system during treatment and these cells also differ by mutation frequency (James et.al.,2002). The stem cells derived from the human embryo is known as Human embryonic stem cells and these cells are for reproductive purpose. While, in 2006 researchers have observed new type of specialized adult cells this cells are called as Induced pluripotent cells (iPSCs). Parthenogenetic stem cells are also one type of stem cells derived from activated human oocytes USES: Stem cells are useful in treating diseases like diabetis and heart diseases and many works are being done on how to use stem cells for cell based therapies in treating diseases which is also called as regenerative medicine. Stem cells have the ability to replace the damaged cells and can be used in treating heart failures. spinal injuries and parkinsons diseases for example, neural stem cells are able tp regenerate nerve tissue damaged by spinal injury. Stem cells are useful in screening toxins in substances such as pesticides and also used during development of new methods for gene therapy that may help those who are suffering from genetic illiness. They are also used in pharmaceutical industry for testing the new drugs before testing on animal and humans. Induced pluripotent cells are the adult stem cells have been genetically remodelled to an embryonic stem like to express genes and factors which maintains the properties of embryonic stem cells. EMBRYONIC AND INDUCED PLURIPOTENT STEM CELLS: Embryonic stem cells are from the earliest stages of human embryo that develop into eggs by invitro fertilization while other embryos are developed for research and extracted after five days growth. It is known that embryonic stem cells divide indefinitely so only a single embryo can form lines of cells to use for treatment.(Thomson et.al.,1998) These cells are undifferentiated but has a ability to differentiate into any cell, tissue or organ in the body. These stem cells can also become nerve, muscle cells or any other type of human cells. The process involved in formation of ES cells is the ovaries are removed and after 76hours of copulation they are treated with media containing serum overnight.The following day the inner cell mass of embryos are removed and cultured on fibroblast after few weeks colonies grew which showed pluripotent characters referred to as ES cells. Embryonic stem cells are used to treat a host of diseases, such as Parkinsons disease, spinal cord injury, and d iabetes (Martins.,1981). For research, these embryos are destroyed in the process of deriving embryonic stem cells. ES cells have got a great potential for long term therapies but the issue arises regarding safety. Transplanted ES cells have uncontrolled growth and could generate tumours which is seen in laboratory cultures by scientists and there are not sure how they behave inside the body. So, this is to be studied before proceeded in clinical trials while another issue is tissues derived from the ES cells are rejected by patients immune system after transplantation. To overcome this issue tissue rejection currently, drugs can be used which suppresses the immune system but these drugs can be infectious thus drugs without any side effects are being investigated by the researchers or alternatively adult stem cells can be used. The major issue is in process of extracting the embryonic cells the embryos have to be destroyed this is opposed by many people and raises ethical issues. Al ternatives are being investigating by combining the stem cell technology with cloning by a method called (SCNT) somatic cell nuclear transfer.(Stewart et.al.,2007). It is a method which involves insertion of the nuclei of the somatic cell into the oocyte which develops into the embryo. This embryo derives the embryonic stem cell lines which is carried out in several mammalian species but till date No ES cells have been successfully developed by this method and also requires destruction of many embryos compared to other methods. And the other issue by usig this method is therauptic human cloning would lead to reproductive human cloning which leads to maral and social danger. The use of ES cells got many ethical issues as it is derived by destroying the embryos which raises fundamental concers of human life. (Tabar et.al.,2001). Problems associated with stem cell research according to the researchers embryonic stem cells are known for the cell baesd therapies as they are more versatile than adult stem cells but the same properties of these cells make them unusual for therapy as these will migrate all over the body and produce tumours. Growing and maintaining embryonic cell lines prove that they are problematic by performing experiments in mice as some of these get mutated and unusable to the patients. To overcome this problem adult stem cells acan be used to eliminate mutation tissue incompatibility. The pharmaceutical companies could not puruse these therapies due to financial incentives ( Phimister and drazen,2004). Recent advances in stem cells have new applications possible for stem cell based technology. It is now possible to reprogram differentiated human somatic cells into pluripotent cells that are functionally equivalent to embryonic stem cells. In 2006, specialized adult cells are been reprogrammed genetically to assume a stem cell like state called as Induced pluripotent stem cells. (Fenno.et.al., 2008). The use of ES cells as an alternative to oocytes which can be reprogrammed as an Human somatic cells. This can be done by fusion of human embryonic stem cells with fibroblasts which results hybrid cells.(Cowan et.al.,2005). These cells exhibits morphology and growth proper of embryonic stem cells and also express their genes. Transplantation of induced pluripotent cells into mice resulted in tumour containing variety of tissues on injection into the blastocyst showed mouse embryonic development This shows that Induced Pluripotent stem cells can be produced from fibroblast on addition wi th defined factors like oct3/4,Sox2 and klf4(Takahashi and Yamanaka.,2006). Researchers have demonstrated a novel technique for production of IPS cells by transforming Adult Skin cells which is considered as a fast reliable and safe method, viruses were used to insert the specific genes into the adult cell would result in increased potential for adverse outcomes and also increases the chance of genetic defects thus it would affect the patient treating with stem cell therapy.(Soldner et.al.,2009) Thus, alternatively transgenes or reprogramming proteins can used for insertion to overcome the risk and after induction using protein factors or virus free factors that can be removed to induce pluripotency which develops into IPS cells that does not have any risk.(Kaji et.al.,2009) As, IPS cells also raises ethical problems related to germline alterations. However using virus free factors can overcome the problem of germline alteration. In 2010, researchers have used Induced pluripotent stem cells to treat rodents suffering with parkinsons disease and this research was successfull this is done by transplanting the induced pluripotent cell neuron into the rodents mid brain injury which is similar to Parkinsons disease in humans by this the cells became functional and showed improvement. Thus induced pluripotent cells may be useful for future disease models and cell-based therapies. Induced pluripotent stem cells offer immense potential for regenerative medicine and studies of development and diseases. Thus analysis of genomic transcriptional activity, gene activation, allele specific gene expression and DNA methylation shows that the somatic cell was reprogrammed to an embryonic state which provides a system for investigating the mechanisms. To Induce pluripotent somatic properties which are similar to ES cells properties is done by introducing active genes or derivatives of RNA or protein products into the somatic cell but this process of acquiring pluripotency is not genetically but involves Epigenomic Reprogramming. There are differences between ES and IPSC cells regarding chromatin structure and gene expressionby showing few similarities while the other reports show that there is epigenetic differences and alteration. Reprogramming of a somatic cell into pluripotent state requires complete change of Somatic cell to an ES cell like state but this is not repo rted yet. On performing genomic profiling of the DNA methylomes of both ES and Induced pluripotent cells similarities are seen but every single line shows different reprogramming variability compared to both ES cells and other Induced pluripotent stem cells. Patterns of DNA methylation are seen as epigenetic change at the tips and centromeres of the chromososmes and show differences in CG methylation and histone modifications. Thus, Induced pluripotent cells may not be suitable substitute for embryonic cells. (Lister et.al., 2011). CONCLUSION: Human embryonic stem (ES) cell research has been the best way for the cell-based therapies for a number of diseases but the issue raises with destroying the embryos to produce these cells. The use of IPS cells has less ethically problematic than the use of Embryonic cells as production Of IPS cells does not require destroying the embryos. But the use of induced pluripotent cells raises ethical concerns to somatic cell reprogramming as there is a difference seen between the ES and Ips cells and the debate over stem cell therapy is increasingly becoming irrelevant but ethical issues regarding the Embryonic stem cells would not entirely go away.So, the study of all the types of stem cells should be done as it is not known which is useful for the cell replacement therapticus.

Nostradamous :: History

Nostradamous Once, while passing through Italy, Nostradamus bowed before a young Franciscan monk, addressing him as "His Holiness." Others around him did not understand his strange behavior and the reasons as to why someone would call a mere monk by such a title. However, years later, and after Nostradamus' death, that monk became Pope Sixtus V. This was just one of the hundreds of prophecies, or visions of the future, that the fifteenth-century prophet made during his lifetime. Nostradamus, born in the year of 1503 in France, spent his childhood under the guidance of his two grandfathers. After going to the University of Montpelier for three years, he received a bachelor's degree in the study of medicine. Around this time, there was an outbreak of the plague in various parts of France, and he quickly earned a good reputation with the use of his medicine. However, Nostradamus' "medicines" were not ordinary, as they consisted of psychological guidance and homemade formulas. Using these methods, he cured many victims of the plague who were previously labeled incurable. He later went back to Montpelier to earn his doctoral degree in medicine. Although Nostradamus was very interested in medicine, he began reading books about the occult and took a fancy to predicting the future. In 1550, he published his first book which contained prophecies for the coming year. The almanac proved so successful and accurate that he began publishing them annually. After several years, Nostradamus developed the idea of writing a complete almanac, entitled Centuries. This book came to consist of prophecies ranging in time from his present to the end of the world. In Centuries there were one thousand quatrains, or verses of four lines each. One which was particularly amazing was this: A Captain of great Germany, Shall come to yield himself by stimulating help, To the Kings of Kings with the help of Hungary, So that his revolt shall cause great bloodshed. This quatrain has been interpreted, in modern day, to mean that Hitler shall involve Hungary in a great battle with much killing. Many believe that it is simply luck that Nostradamus had in predicting the future because his prophecies are generalized and not exact. However, one of his writings contained the man "Hister" who was to be very powerful in a revolt. This obviously bears much resemble to Hitler, and if this is true, Nostradamus clearly predicted someone that was not to be born until more than three

Walmart Stores Inc.

Management Control Systems Assignment Case study: A) Wal-Mart Stores, Inc. , Case 1-2, Page no. 31 B) Vershire Company, Case 4-1, Page no. 145 Case A) Wal-Mart Stores, Inc. Question 1. What is Wal-Mart’s strategy? What is the basis on which Wal-Mart builds its competitive advantage? Answer? Wal-Mart’s Strategy is a. Winning strategy of Wal-Mart is based on selling branded products at a low cost. b. Marketing strategy of Wal-Mart is â€Å"Everyday low prices† is to pull in customers everyday. c. Saturation strategy of Wal-Mart is for the store expansion. The standards was to be able to drive from a distribution centre to store within a day.And a distribution centre was strategically planned so that it eventually serve 150-200 stores within a day’s drive. d. Bulk strategy of Wal-Mart is for purchasing branded products at bulk can help to drive hard bargain which help Wal-Mart to sell the products at low prices. These are the main basic policies which Wal-Mar t follows to become world’s largest retailer. On the basis of selling branded products at low cost and everyday low prices at Wal-Mart store and also continuously following the above strartegies helps Wal-Mart builds its competitive advantage over other retail stores to pull in more customers everyday.Question 2. How do Wal-Mart’s control systems help execute the firm’s strategy? Answer? The Wal-Mart’s control systems help execute the firm’s strategy is given below, †¢The Information Technology- The IT that powered Wal-Mart’s supply chain and logistics was the most powerful. Therefore it pursuads its suppliers to adapt latest supply chain technologies like RFID- which increases monitoring and management of the inventory. †¢Each distribution center 24 operated hours a day using laser-guided conveyer belts and cross-docking techniques that received goods on one side and simultaneously filling orders on other side. The Wal-Mart had la rgest privately owned satellite communication network in US and broadcasted television. †¢Each store constituted an investment centre and was evaluated on its profits relative to its inventory investments. †¢The data from â€Å"outstanding† performers among 5300 stores were used to improve operations in â€Å"problem† stores. †¢For the employees loyalty and dedication- the Wal-Mart offers Profit sharing for the employees who spends at least one year and who worked at least 1000 hours. Several policies that help Wal-Mart to execute the firm’s strategy such as- incentive bonuses, a discounted stock purchase plan, promotion from within, pay rises based on performance not on seniority basis, open door policy . †¢Wal-Mart had implemented a satellite network system that allowed information to be shared between companies wide network of stores, distribution centers and suppliers. By following these above mentioned control systems it help to execute the Wal-Mart’s strategy.

Misbehavior: Automobile and Consequences Essay

Every child misbehaves in their life. Whether it be one time or a thousand times. It teaches us a lesson. Without misbehavior we wouldn’t know what is right and what is wrong. Once we act and do something wrong, we learn and move on from our mistakes, knowing what the right choice is. In my life I have misbehaved and done numerous things that were wrong. However, I am somewhat grateful that I did these wrong things because without doing them and receiving consequences I wouldn’t know the difference between right and wrong. This essay is one example of how I have misbehaved at one point in my life. In June of 2003, I was six, almost 7. I had the knowledge that I probably shouldn’t try and control a car by myself. However, I had been behind the wheel a few times and would control the wheel while either on my father’s or mother’s lap. I knew how to control most things, the gas, the gear shift, the seat controls. I also thought I knew how to control the brakes; however I might have been wrong. All of these things led me to believe that I could control the car without being supervised. I had some idea that it wasn’t right to get in the driver seat but I didn’t think the consequences would be that bad, even if I did succeed. I decided to do it. My mom had just gone inside; she had left something in the house that she needed to get. She left the keys in the ignition. I saw this as an opportunity to back up the car. I made my way from the back seat to the front by jumping over the middle consul; I knew I didn’t have much time, so I tried to be as quick as possible. I put my foot on the brake, preparing myself for when I switched gears. As I shifted from park to reverse nerves suddenly came over me. I felt fear. Due to my nerves and fear I became overwhelmed and put way too much pressure on the gas pedal. The next thing I remember is me hitting a tree that was about 15 feet behind where the car was originally parked. As I panicked, I saw my mother, running out of the house. Vaus1 My mother was going to be mad, I just didn’t know how mad exactly. I had made a mistake that I couldn’t take back. My mother however, was more concerned about me than the damage done to the car. She checked to see if I was okay, I was fine. Next she checked the back of the car where she discovered a HUGE dent. Surprisingly my mother remained calm and didn’t freak out like I assumed she would. I was then sent to my bedroom where I anxiously awaited my mother’s entrance. Finally she came in and talked to me. I had consequences, but not too serious. I was grounded from seeing friends, playing video games, and watching tv or anything like that. I believe my consequences were not that bad and I am thankful for this experience. If I didn’t do what I had done I would not have learned this important lesson that I will always remember.